Concepedia

Pertactin-Negative Bordetella pertussis Strains: Evidence for a Possible Selective Advantage

Stacey W. Martin, Lucia C. Pawloski, Margaret M. Williams, K. Weening, Chas DeBolt, Xuan Qin, Laura Reynolds, Carol Kenyon, G. Giambrone, Kathy Kudish,

Clinical Infectious Diseases · 2014 · 191 citations · 23 references

DOIFull text

Open access

Abstract

The significant association between vaccination and isolate pertactin production suggests that the likelihood of having reported disease caused by PRN(-) compared with PRN(+) strains is greater in vaccinated persons. Additional studies are needed to assess whether vaccine effectiveness is diminished against PRN(-) strains.

References

23

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Jason M. Warfel, Lindsey I. Zimmerman, Tod J. Merkel · Proceedings of the National Academy of Sciences · 2013 · 622 citations · Full text

Waning Protection after Fifth Dose of Acellular Pertussis Vaccine in Children

Nicola P. Klein, Joan Bartlett, Ali Rowhani‐Rahbar et al. · New England Journal of Medicine · 2012 · 570 citations · Full text

<i>Bordetella pertussis</i>Strains with Increased Toxin Production Associated with Pertussis Resurgence

Frits R. Mooi, Inge H. M. van Loo, Marjolein van Gent et al. · Emerging infectious diseases · 2009 · 340 citations · Full text

Number and Order of Whole Cell Pertussis Vaccines in Infancy and Disease Protection

Sarah Sheridan, Robert S. Ware, Keith Grimwood et al. · JAMA · 2012 · 272 citations

Association of Childhood Pertussis With Receipt of 5 Doses of Pertussis Vaccine by Time Since Last Vaccine Dose, California, 2010

Lara Misegades, Kathleen Winter, Kathleen Harriman et al. · JAMA · 2012 · 254 citations