The reaction of o-phenylenediamine with α,β-unsaturated carbonyl compounds

Abstract

The structures of the products obtained by the reaction of o-phenylenediamine and two isomeric chalcones have been identified as 1,5-benzodiazepines. A 1 H, 13 C and 15 N NMR study in solution combined with B3LYP/6-31G** calculations allowed to determine the conformations present in solution.