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Hypoxia Increases LDL Oxidation and Expression of 15-Lipoxygenase-2 in Human Macrophages

DOI

87

Citations

32

References

2004

Year

Ellen Knutsen Rydberg, Alexandra Krettek, Christina Ullström, Karin M. Ekström, Per‐Arne Svensson, Lena Carlsson, Ann‐Cathrine Jönsson‐Rylander, Göran I. Hansson, William L. McPheat, Olov Wiklund,
Arteriosclerosis Thrombosis and Vascular Biology

Abstract

In summary, these observations show for the first time that 15-LOX-2 is expressed in hypoxic macrophages and in atherosclerotic plaques and suggest that 15-LOX-2 may be one of the factors involved in macrophage-mediated LDL oxidation at hypoxia.

References

YearCitations

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