BJOG An International Journal of Obstetrics & Gynaecology · 1988 · 47 citations · 18 references
MedicineGynecologyObstetricsMaternal-fetal MedicineReproductive ImmunologyReproductive MedicinePregnancyPregnancy ImmunologyRecurrent Pregnancy LossGestation PeriodRecurrent Miscarriage ImmunologyRecurrent Miscarriage RiskTrophoblast ImmunologyTrophoblast-immune Cell InteractionsUnexplained Recurrent Pregnancy Loss
A novel protocol is described which has been developed for immunotherapy in unexplained recurrent miscarriage. This is based on a single intravenous infusion with isolated placental trophoblast plasma membrane vesicle preparations. Clinical experience gained with this approach is described. A total of 16/21 (76%) patients who subsequently had pregnancies have now achieved a live birth or are currently pregnant at greater than 28 weeks gestation.
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Preparation of human placental villous surface membrane
NANCY C. SMITH, M. G. Brush, SUSAN LUCKETT · Nature · 1974 · 249 citations
A. E. Beer, A.E. Semprini, Xiao-yong Zhu et al. · PubMed · 1985 · 151 citations
Immunologic Testing and Immunotherapy in Recurrent Spontaneous Abortion
JOHN A. McINTYRE, Page Faulk, Victoria Nichols-Johnson et al. · Obstetrics and Gynecology · 1986 · 117 citations