<i>Plasmodium falciparum</i>Intercellular Adhesion Molecule–1–Based Cytoadherence‐Related Signaling in Human Endothelial Cells

Abstract

Signaling via apposition of P. falciparum-infected erythrocytes with host endothelium is dependent, at least in part, on the cytoadherence characteristics of the invading isolate. An understanding of the postadhesive processes produced by cytoadherence may help us to understand the variable pathologies seen in malaria disease.