Role of glycogen synthase kinase-3β in ketamine-induced developmental neuroapoptosis in rats

Subanesthetic Effects of the Noncompetitive NMDA Antagonist, Ketamine, in Humans

John H. Krystal · Archives of General Psychiatry · 1994 · 3.3K citations

Blockade of NMDA Receptors and Apoptotic Neurodegeneration in the Developing Brain

Chrysanthy Ikonomidou, Friederike Bosch, Michael Miksa et al. · Science · 1999 · 2K citations

Ketamine anesthesia during the first week of life can cause long-lasting cognitive deficits in rhesus monkeys

Merle G. Paule, M. Li, Richard R. Allen et al. · Neurotoxicology and Teratology · 2011 · 564 citations · Full text

Behavioral Neuroscience, Neurophysiology, Rhesus Monkeys +11

Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons

E Chalecka-Franaszek, De‐Maw Chuang · Proceedings of the National Academy of Sciences · 1999 · 539 citations

Neurotransmitter, Cell Death, Neurotransmission +19

Anesthesia induces neuronal cell death in the developing rat brain via the intrinsic and extrinsic apoptotic pathways

Jun Heum Yon, J. Daniel-Johnson, L.B. Carter et al. · Neuroscience · 2005 · 464 citations

Neuronal Cell Death, Anesthetic Mechanism, Cell Death +16