Mechanisms Involved in Extraterritorial Facial Pain following Cervical Spinal Nerve Injury in Rats

Abstract

The present findings have demonstrated that mechanical allodynia and thermal hyperalgesia occur in the lateral facial skin after CNX and also suggest that ERK phosphorylation of Vc and C1-C2 neurons and astroglial cell activation are involved in orofacial extraterritorial pain following cervical nerve injury.