Catalytic and Enantioselective α‐Functionalization of Oxindoles Through Oxidative Reactions with Naphthoquinones

Abstract

Strong as an oxindole: The enantioselective assembly of 3,3-disubstituted oxindoles is an attractive and valuable target because of the unique properties of the oxindole core. A new organocatalyzed and enantioselective aerobic oxidative strategy for the assembly of this core structure from oxindoles and simple naphthoquinones is reported (see scheme).