Eicosapentaenoic acid ameliorates diabetic nephropathy of type 2 diabetic KKAy/Ta mice: Involvement of MCP-1 suppression and decreased ERK1/2 and p38 phosphorylation - Concepedia

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Eicosapentaenoic acid ameliorates diabetic nephropathy of type 2 diabetic KKAy/Ta mice: Involvement of MCP-1 suppression and decreased ERK1/2 and p38 phosphorylation

83

Citations

17

References

2005

Year

Shinji Hagiwara, Yuichiro Makita, Leyi Gu, Mitsuo Tanimoto, Minfang Zhang, Shinji Nakamura, Shigeru Kaneko, Takamichi Itoh, Tomohito Gohda, Satoshi Horikoshi,

Nephrology Dialysis Transplantation

Abstract

EPA ameliorates diabetic nephropathy of type 2 diabetic KKAy/Ta mice. We propose that the observed down-regulation of MCP-1 is critically involved in the beneficial effect of EPA, probably in concert with improvement of other clinical parameters.

References

	Year	Citations

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