Immunohistochemistry for PMS2 and MSH6 alone can replace a four antibody panel for mismatch repair deficiency screening in colorectal adenocarcinoma

Revised Bethesda Guidelines for Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome) and Microsatellite Instability

Asad Umar, C. Richard Boland, Jonathan P. Terdiman et al. · JNCI Journal of the National Cancer Institute · 2004 · 3.2K citations · Full text

Life Sciences, Genetics, Oncology +17

Feasibility of Screening for Lynch Syndrome Among Patients With Colorectal Cancer

Heather Hampel, Wendy L. Frankel, Edward W. Martin et al. · Journal of Clinical Oncology · 2008 · 871 citations

Medicine, Oncology, Pathology +17

Molecular Characterization of MSI-H Colorectal Cancer by <i>MLHI</i> Promoter Methylation, Immunohistochemistry, and Mismatch Repair Germline Mutation Screening

Jenny N. Poynter, Kimberly D. Siegmund, Daniel J. Weisenberger et al. · Cancer Epidemiology Biomarkers & Prevention · 2008 · 228 citations · Full text

Life Sciences, Genetics, Oncology +17

Immunohistochemical Analysis Reveals High Frequency of PMS2 Defects in Colorectal Cancer

Kaspar Truninger, Mirco Menigatti, Judith Luz et al. · Gastroenterology · 2005 · 218 citations

Medicine, Oncology, Pathology +11

Use of Molecular Tumor Characteristics to Prioritize Mismatch Repair Gene Testing in Early-Onset Colorectal Cancer

Melissa C. Southey, Mark A. Jenkins, Leeanne J. Mead et al. · Journal of Clinical Oncology · 2005 · 213 citations · Full text

Life Sciences, Genetics, Oncology +17