Concepedia

The Wittig Reaction Using Potassium-tert-butoxide High Yield Methylenations of Sterically Hindered Ketones

Lutz Fitjer, Ulrike Quabeck

Synthetic Communications · 1985 · 145 citations · 21 references

DOI

Concepts

Abstract

Abstract Potassium-tert-butoxide is recommended for general use in Wittig reactions with nonstabilized ylides. High yield methylenations of cyclohexanone and a series of five sterically hindered ketones demonstrate its utility.

References

21

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