Journal of Materials Chemistry B · 2013 · 485 citations · 144 references
PharmacyBiomedical EngineeringPharmaceuticsBiocompatibilityBiomaterialsDrug DeliveryBrain Targeted DeliveryDrug Delivery BiomaterialsDrug Delivery SystemsGelsHydrogel BiomaterialsHydrogelsControlled Drug ReleaseDrug Delivery HydrogelsDrug Delivery PolymersHydrogel Delivery SystemsHydrogel Drug Delivery SystemsHydrogel-based DeliveryHydrogel-based Delivery SystemsHydrogel-based Systems
The growing demand for targeted controlled drug delivery has spurred the development of biomaterials with enhanced biocompatibility and biodegradability, including smart polymers that compete with traditional hydrogel systems. The article aims to highlight the diverse applications of hydrogels in drug delivery, summarize their role as delivery vehicles for brain and other disorders, and discuss limitations and future prospects. It reviews hydrogels as delivery vehicles for brain and other disorders, their clinical applications and toxicological aspects, and examines limitations and future prospects. The review identifies hydrogels’ potential for diagnostics and therapeutic interventions against tuberculosis.
The upsurge in the need of targeted controlled drug delivery (TCDD) has led to the invention of remarkable biomaterials with improved biocompatibility and biodegradability. In recent years, “Smart Polymers” have emerged as a potential candidate, competing with the existing hydrogel systems used for controlled drug delivery. This article is an effort to highlight the diverse applications of hydrogels for revolutionizing the present research on drug delivery systems. This article summarizes the role of hydrogels as delivery vehicles for drugs used in various disorders related to the brain and other distinct parts of the human body. The clinical application and toxicological aspects of hydrogels are also highlighted. Their potential for diagnostics and various therapeutic interventions against tuberculosis have been reviewed. In addition, the limitations and future prospectives in the development of biopolymeric hydrogels are discussed.
144
Environment-sensitive hydrogels for drug delivery
Yong Qiu, Kinam Park · Advanced Drug Delivery Reviews · 2012 · 849 citations
P.T. Sudheesh Kumar, Vinoth‐Kumar Lakshmanan, T.V. Anilkumar et al. · ACS Applied Materials & Interfaces · 2012 · 752 citations
Natural Sciences, Biomedical Engineering, Materials Science +17