BMJ Case Reports · 2011 · 15 citations · 11 references
PharmacyCardiologyPharmacotherapyAgingCardiovascular PharmacotherapyGeriatric PharmacotherapyCardiovascular AgingCardiovascular DiseaseCardiovascular Pharmacotherapy In Older AdultsCardiovascular Toxicity In Older AdultsHeart FailureSteroid PharmacologyAge-related Cardiac RiskAge-related Cardiovascular ChangesAnabolic Androgenic Steroid AbuseAnabolic Androgenic SteroidsAnabolic-androgenic Steroid UseCardiovascular Drug ToxicitySteroid Adverse EffectsYoung Adulthood
Widespread use of anabolic androgenic steroid (AAS) abuse is a rapidly increasing public health concern with an expanding demographic. Previous studies and reports have been exclusive to young individuals at low risk for traditional, non-AAS associated, cardiovascular disease. To date, the impact of AAS use on older patients has not been well characterised. The patient herein presented documents a dramatic case of an older individual who developed decompensated heart failure secondary to illicit use of AAS, highlighting an evolving problem among a rapidly expanding demographic and illustrating that a) AAS, used to alter appearance or augment performance, is no longer an issue confined to young adults; b) older individuals with ageing myocardium may be particularly susceptible to AAS toxicity and may present with fulminate congestive heart failure; and that c) AAS abstinence coupled with traditional heart failure pharmacotherapy may be an effective treatment for this condition.
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Are the cardiac effects of anabolic steroid abuse in strength athletes reversible?
Axel Urhausen · Heart · 2004 · 271 citations · Full text
High-Density—Lipoprotein Cholesterol in Bodybuilders v Powerlifters
Ben F. Hurley · JAMA · 1984 · 100 citations