American Journal of Psychiatry · 1946 · 33 citations · 5 references
MedicineNeurosciencePsychiatryClinical NeuroscienceNeuroanatomyNeuropsychiatryNeuropsychiatric DisordersPsychosomatic MedicineSchizophrenia Spectrum DisordersOrbitofrontal Syndrome
1. The orbital cortex was partly isolated on 22 schizophrenics, and good response was observed where there were symptoms of introversion, blockage, emotional dulling and depersonalisation present. 2. The isolation of the orbital lobe produced a triad of symptoms described as: extroversion, increased motor activity and euphoria. 3. It was emphasised that the new symptoms produced, balance well with the pre-existing psychotic symptoms.
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Physiology of the Nervous System
John F. Fulton · Science · 1939 · 355 citations
THE FUNCTIONAL ORGANIZATION OF THE CEREBRAL CORTEX
Warren S. McCulloch · Physiological Reviews · 1944 · 135 citations
Stanley Cobb · The American Journal of the Medical Sciences · 1943 · 56 citations