Palladium‐Catalyzed Hydrobenzylation of <i>ortho</i>‐Tolyl Alkynyl Ethers by Benzylic CH Activation: Remarkable Alkynoxy‐Directing Effect

Abstract

It's selective: The title reaction involves palladium(0)-catalyzed insertion of CC bonds into benzylic C(sp3)H bonds, thus providing efficient access to 2-methylene-2,3-dihydrobenzofurans, which transform into benzofurans upon treatment with a weak acid (e.g., AcOH) and electrophiles. The alkynoxy group serves as a directing group in promoting CH bond functionalization. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.