Highly Efficient Stereoselective Catalytic C(sp³)H Insertions with Donor Rhodium Carbenoids Generated from Cyclopropenes

Abstract

Rings of five and six: Donor alkenyl rhodium carbenoids generated from 3,3-dimethylcyclopropenylcarbinols exhibit high reactivity in intramolecular CH insertions. The reactions proceed under remarkably mild conditions, tolerate the presence of the free hydroxy group, and afford an efficient and stereoselective access to a variety of functionalized carbocycles and oxygen heterocycles.