Dentistry · 2013 · 12 citations · 24 references
DentistryPeriodonticsPeriodontologyPeriodontal BiologyPeriodontal GeneticsCongenital Oral AnomaliesDevelopmental Dental AnomaliesGingival DiseasePeriodontal DiseasePeriodontal Tissue PathologyAutosomal Recessive InheritanceDental AbnormalitiesEpidermal HyperkeratosisExfoliationHereditary Dental DisordersPapillon-lefèvre SyndromePeriodontal LesionsPrimary Dentition Involvement
Papillon-Lefevre syndrome is a rare autosomal recessive genetic disorder. The clinical manifestations include palmer planter hyperkeratosis with precocious progressive periodontal disease that results in premature exfoliation of primary and permanent dentitions. Patients are often edentulous at an early age.
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