A Multicenter Comparison of Polymyxin B Sulfate/Trimethoprim Ophthalmic Solution and Moxifloxacin in the Speed of Clinical Efficacy for the Treatment of Bacterial Conjunctivitis

Abstract

Moxifloxacin 0.5% administered three times daily is safe and cures bacterial conjunctivitis more effectively and significantly faster than polymyxin/trimethoprim dosed four times daily. The majority of patients were cured and symptom-free by 48 hours. Therefore, moxifloxacin is cost-effective and significantly more efficacious than polymyxin/trimethoprim in the speed by which it reduces the symptoms and disease transmission.