Concepedia

Lentivirus-mediated shRNA Interference Targeting SLUG Inhibits Lung Cancer Growth and Metastasis

Yao-Peng Wang, Mingzhao Wang, Yi-Ren Luo, Yi Shen, Zhao-Xia Wei

Asian Pacific Journal of Cancer Prevention · 2012 · 17 citations · 15 references

DOIFull text

Open access

Abstract

These results indicate that SLUG is a newly identified gene associated with lung cancer growth and metastasis. SLUG may serve as a new therapeutic target for the treatment of lung cancer in the future.

References

15

Tumour invasion and metastasis initiated by microRNA-10b in breast cancer

Li Ma, Julie Teruya‐Feldstein, Robert A. Weinberg · Nature · 2007 · 2.6K citations

, , +9

A rapid in vitro assay for quantitating the invasive potential of tumor cells.

Adriana Albini, Yukihide Iwamoto, Kleinman Hk et al. · PubMed · 1987 · 1.8K citations

, , +18

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

Douglas A. Rubinson, Christopher P. Dillon, Adam V. Kwiatkowski et al. · Nature Genetics · 2003 · 1.5K citations

, , +9

Slug Expression in the E-cadherin Preserved Tumors Is Related to Prognosis in Patients with Esophageal Squamous Cell Carcinoma

Yasuto Uchikado, Shoji Natsugoe, Hiroshi Okumura et al. · Clinical Cancer Research · 2005 · 186 citations · Full text

Epithelial-mesenchymal transition, the tumor microenvironment, and metastatic behavior of epithelial malignancies.

Lindsay J. Talbot, Syamal D. Bhattacharya, Paul C. Kuo · PubMed · 2012 · 170 citations · Full text