Rational Molecular Design of Stimulus‐Responsive Supramolecular Hydrogels Based on Dipeptides

Abstract

Stimuli-responsive supramolecular hydro­gels comprising self-assembled nanofiber networks are attractive soft materials because of their potential application in materials science and bionanotechnology. Here, we describe a general strategy for the rational design of stimuli (redox- or photo-)responsive supramolecular hydrogelators by introducing stimuli-triggered degradation units into the N-terminal of a dipeptide. We also demonstrate that its coupling with glucose oxidase allows us to produce a glucose-responsive insulin-releasing gel matrix. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.