Safety and Pharmacokinetic Effects of TNP-470, an Angiogenesis Inhibitor, Combined With Paclitaxel in Patients With Solid Tumors: Evidence for Activity in Non–Small-Cell Lung Cancer - Concepedia

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Safety and Pharmacokinetic Effects of TNP-470, an Angiogenesis Inhibitor, Combined With Paclitaxel in Patients With Solid Tumors: Evidence for Activity in Non–Small-Cell Lung Cancer

102

Citations

28

References

2002

Year

Roy S. Herbst, Timothy Madden, Hai T. Tran, George R. Blumenschein, Christina A. Meyers, Lee F. Seabrooke, Fadlo R. Khuri, Vinay K. Puduvalli, Victoria Allgood, Herbert A. Fritsche,

Journal of Clinical Oncology

Abstract

The combination of TNP-470 and paclitaxel, each at full single-agent dose, seems well tolerated, with minimal pharmacokinetic interaction between the two agents. Further studies of TNP-470 with chemotherapy regimens are warranted in NSCLC and other solid tumors.

References

	Year	Citations

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