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Publication | Open Access

Targeted Inhibition of Calpain Reduces Myocardial Hypertrophy and Fibrosis in Mouse Models of Type 1 Diabetes

DOIFull Paper Access

116

Citations

37

References

2011

Year

Ying Li, Jian Ma, Huaqing Zhu, Manpreet K. Singh, David J. Hill, Peter A. Greer, J. Malcolm O. Arnold, E. Dale Abel, Tianqing Peng
Diabetes

Abstract

Myocardial hypertrophy and fibrosis in diabetic mice are attenuated by reduction of calpain function. Thus targeted inhibition of calpain represents a potential novel therapeutic strategy for reversing diabetic cardiomyopathy.

References

YearCitations

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