Sequential research-related biopsies in phase I trials: acceptance, feasibility and safety

Dose- and Schedule-Dependent Inhibition of the Mammalian Target of Rapamycin Pathway With Everolimus: A Phase I Tumor Pharmacodynamic Study in Patients With Advanced Solid Tumors

Josep Tabernero, Federico Rojo, Emiliano Calvo et al. · Journal of Clinical Oncology · 2008 · 532 citations

Medicine, Oncology, Pharmacology +17

Guidelines for the Development and Incorporation of Biomarker Studies in Early Clinical Trials of Novel Agents

Janet Dancey, Kevin K. Dobbin, Susan Groshen et al. · Clinical Cancer Research · 2010 · 257 citations · Full text

Pharmacy, Pharmacology, Clinical Pharmacology +16

Prospective Validation of a Prognostic Score to Improve Patient Selection for Oncology Phase I Trials

Hendrik‐Tobias Arkenau, Jorge Barriuso, David Olmos et al. · Journal of Clinical Oncology · 2009 · 207 citations · Full text

Medicine, Oncology, Metastasis +14

Pharmacodynamic Studies of Gefitinib in Tumor Biopsy Specimens From Patients With Advanced Gastric Carcinoma

Federico Rojo, Josep Tabernero, Joan Albanell et al. · Journal of Clinical Oncology · 2006 · 137 citations · Full text

Medicine, Oncology, Pharmacology +17

Impact and Perceptions of Mandatory Tumor Biopsies for Correlative Studies in Clinical Trials of Novel Anticancer Agents

Mark Agulnik, Amit M. Oza, Gregory R. Pond et al. · Journal of Clinical Oncology · 2006 · 98 citations

Medicine, Clinical Sciences, Oncology +13