Nuclear Factor-κB Nuclear Localization Is Predictive of Biochemical Recurrence in Patients with Positive Margin Prostate Cancer

Abstract

In univariate and multivariate analysis, NF-kappaB nuclear expression was strongly predictive of biochemical recurrence in patients with positive surgical margins after RP. We propose that nuclear NF-kappaB may serve as a useful independent molecular marker for stratifying patients at risk for recurrence.