Regioselective C_sp2–H dual functionalization of indoles using hypervalent iodine(<scp>iii</scp>): bromo-amination via 1,3-migration of imides on indolyl(phenyl)iodonium imides

Abstract

A regioselective C(sp(2))-H dual functionalization of indoles, which underlies bromo-amination via the 1,3-migration of imide groups on indolyl(phenyl)iodonium imides as novel imide-combined hypervalent iodines(III), has been developed to provide 2-bis(sulfonyl)amino-3-bromo-indoles under the metal-free conditions.