Synthesis and Characterization of New Functional Poly(ester‐anhydride)s Based on Succinic and Sebacic Acids

Abstract

Abstract Summary: New functional poly(ester‐anhydride)s with allyl pendant groups in the side chains were obtained by polycondensation of sebacic acid (SBA) and poly(3‐allyloxy‐1,2‐propylene succinate) (OSAGE) terminated with carboxyl groups. The carboxyl groups in OSAGE and in SBA were converted to mixed anhydride groups by acetylation with acetic anhydride. After that, prepolymers obtained were condensed in vacuum to yield higher molecular weight poly(ester‐anhydride)s. The influence of SBA and OSAGE content in poly(ester‐anhydride)s on their selected properties e.g. molecular weight, thermal and solubility characteristics as well as degradation rate and mode, were examined. Poly(ester‐anhydride)s were degraded in aqueous buffer of pH 7.4 at 37 °C. The hydrolytic degradation was monitored by determination of weight loss of samples and by determination of ester to anhydride groups ratio.