Activated Nitriles in Heterocyclic:Synthesis Novel Syntheses of Imidazo[2,1-<i>b</i>]-1,3-Thiazine Derivatives

Abstract

Abstract Several new imidazo[2,1-b]-1,3-thiazine derivatives 4a–c, 8a–c, and 11a–c were synthesised via the reaction of 5,5-diphenyl-2-thiohydantoin (1) with αβ -unsaturated nitriles 2a–c, 5a–c, and 9a–c. The structures of the products were established on the basis of elemental analyses, IR, and 1H-NMR spectral data.