Antimicrobial Agents and Chemotherapy · 2005 · 75 citations · 12 references
Life SciencesMicrobiologyMolecular GeneticsBacteriologyMedical MicrobiologyMicrobial GeneticsAntibiotic Resistance GeneticsBacterial EpidemiologyBacterial GeneticsMolecular Epidemiology Of ResistancePathogen DetectionPathogen GenomicsBacterial DetectionEscherichia ColiEscherichia Coli ResistanceGenotypic Characterization Of IsolatesMolecular Detection Of BacteriaResistance Gene-mediated ResistanceResistance In Clinical Isolates
qnr was detected in 2 of 260 Escherichia coli clinical isolates collected from a Korean hospital during the period 2001 to 2003. The two strains were not clonally related. qnr was located in In4 family class 1 integrons of original structure, downstream of orf513 and upstream from another resistance gene (dfrA3b) and a gene of unknown function (orf105). Transfer of the qnr determinant by conjugation could be detected from only one strain.
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Mechanisms of fluoroquinolone resistance
David C. Hooper · Drug Resistance Updates · 1999 · 488 citations