Schizodeme analysis of Trypanosoma cruzi stocks from South and Central America by analysis of PCR-amplified minicircle variable region sequences

Genetic analysis of amplified DNA with immobilized sequence-specific oligonucleotide probes.

Randall K. Saiki, P. Sean Walsh, C. Levenson · Proceedings of the National Academy of Sciences · 1989 · 1K citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Base composition-independent hybridization in tetramethylammonium chloride: a method for oligonucleotide screening of highly complex gene libraries.

William I. Wood, Jane Gitschier, L A Lasky et al. · Proceedings of the National Academy of Sciences · 1985 · 810 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +14

Natural populations of Trypanosoma cruzi, the agent of Chagas disease, have a complex multiclonal structure.

Michel Tibayrenc, Peter Ward, Andrés Moyá et al. · Proceedings of the National Academy of Sciences · 1986 · 405 citations · Full text

Life Sciences, Biology, Genetics +11

Strains and clones of Trypanosoma cruzi can be characterized by pattern of restriction endonuclease products of kinetoplast DNA minicircles.

Carlos Morel, E Chiari, Erney P. Camargo et al. · Proceedings of the National Academy of Sciences · 1980 · 346 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +12

Sensitive detection and schizodeme classification of Trypanosoma cruzi cells by amplification of kinetoplast minicircle DNA sequences: use in diagnosis of Chagas' disease

Nancy R. Sturm, Wim Degrave, Carlos Morel et al. · Molecular and Biochemical Parasitology · 1989 · 313 citations · Full text

Veterinary Medicine, Microbiology, Molecular Biology +13