Publication | Closed Access
Synthesis, DNA binding, docking and photocleavage studies of quinolinyl chalcones
16
Citations
80
References
2014
Year
Combinatorial ChemistryBioorganic ChemistryDna BindingPhotochemistryNatural SciencesMechanistic PhotochemistrySimple Quinoline–chalcone ConjugatesOligonucleotideMolecular BiologyOrganic ChemistryChemistryPromising Dna BindingHeterocycle ChemistryPharmaceutical ChemistrySynthetic ChemistryNucleolytic Activity
A series of simple quinoline–chalcone conjugates have been synthesized and evaluated for their nucleolytic activity. The compounds <bold>3c</bold> and <bold>3d</bold> exhibited promising DNA binding and DNA photocleavage studies.
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