Haplotype Analysis Reveals Founder Effects of Thyroglobulin Gene Mutations C1058R and C1977S in Japan - Concepedia

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Publication | Open Access

Haplotype Analysis Reveals Founder Effects of Thyroglobulin Gene Mutations C1058R and C1977S in Japan

DOI Full Paper Access

77

Citations

15

References

2006

Year

Akira Hishinuma, Shuji Fukata, Soroku Nishiyama, Yoshikazu Nishi, Masamichi Ohishi, Yoshiharu Murata, Yoshihide Ohyama, Nobuo Matsuura, Kikuo Kasai, Shohei Harada,

The Journal of Clinical Endocrinology & Metabolism

Abstract

The frequently found mutations, C1058R and C1977S, were caused by founder effects. This result suggests that Tg mutations may provide a genetic basis for the cause of familial euthyroid goiter.

References

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