Dynamic Contrast-enhanced MR Imaging of Uterine Cervical Cancer: Pharmacokinetic Analysis with Histopathologic Correlation and Its Importance in Predicting the Outcome of Radiation Therapy

Abstract

Areas of increased contrast enhancement are mainly composed of abundant cancer cell fascicles, whereas poorly perfused areas are composed of fibrous tissue with scattered cancer cells. Radiation therapy is more effective in well-enhanced tumors, resulting in improved local control.