Physics in Medicine and Biology · 2015 · 134 citations · 16 references
EngineeringNuclear EngineeringNuclear MedicineDiagnostic ImagingRadiation DetectionRadiation MeasurementDetector TechnologyGamma-ray DetectionPositron Emission TomographyPositron Emission Tomography PhysicsRadiation Imaging DetectorsScintillation DetectorsNoise SuppressionPositron Emission Tomography DetectionPositron Emission Tomography ScintillatorsTime ResolutionTime-of-flight ImagingTime-of-flight PetTime-of-flight Positron Emission TomographyTime-of-flight Timing Resolution
The coincidence time resolution (CTR) becomes a key parameter of 511 keV gamma detection in time of flight positron emission tomography (TOF-PET). This is because additional information obtained through timing leads to a better noise suppression and therefore a better signal to noise ratio in the reconstructed image. In this paper we present the results of CTR measurements on two different SiPM technologies from FBK coupled to LSO:Ce codoped 0.4%Ca crystals. We compare the measurements performed at two separate test setups, i.e. at CERN and at FBK, showing that the obtained results agree within a few percent. We achieve a best CTR value of 85 ± 4 ps FWHM for 2 × 2 × 3 mm(3) LSO:Ce codoped 0.4%Ca crystals, thus breaking the 100 ps barrier with scintillators similar to LSO:Ce or LYSO:Ce. We also demonstrate that a CTR of 140 ± 5 ps can be achieved for longer 2 × 2 × 20 mm(3) crystals, which can readily be implemented in the current generation PET systems to achieve the desired increase in the signal to noise ratio.
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Time of flight in PET revisited
W.W. Moses · IEEE Transactions on Nuclear Science · 2003 · 335 citations