JAUNDICE IN MUCOVISCIDOSIS (FIBROCYSTIC DISEASE OF PANCREAS)<subtitle>Report of Four Cases</subtitle>

Abstract

ALTHOUGH pathologic changes in the liver, varying from fatty metamorphosis to biliary cirrhosis, are not uncommon in fibrocystic disease, jaundice is ordinarily regarded as an unusual symptom of this disease. From 1922 to Jan. 1, 1954, at the Indiana University Medical Center 6741 autopsies were done. Of these, 3517 were performed on children 15 years of age or less. In this series of autopsies, there were 14 cases of fibrocystic disease of the pancreas, in 4 of which jaundice was a chief complaint. In all four of these cases, confirmatory laboratory evidence of hyperbilirubinemia was obtained. The relative infrequency of jaundice in fibrocystic disease of the pancreas prompted the presentation of the findings in these cases. <h3>REPORT OF CASES</h3> Case1.—M. G., a four-day-old white baby girl, had had no bowel movements since birth and was brought to the Medical Center on Feb. 19, 1949, with icterus and signs of