Attenuated Myocardial Vasodilator Response in Patients With Hypertensive Hypertrophy Revealed by Oxygenation-Dependent Magnetic Resonance Imaging

Abstract

Patients with hypertensive hypertrophy demonstrate an impaired ability to increase intramyocardial oxygenation during vasodilatory stress, as indexed by BOLD MRI. The capacity to image vascular function with BOLD MRI may advance the understanding of the development of ventricular dysfunction in hypertension.