Publication | Closed Access
Immobilized Biomaterials—Techniques and Applications
49
Citations
74
References
1982
Year
Tissue EngineeringEngineeringMultifunctional BiomaterialsBiofabricationWhole CellsBiomedical EngineeringEnzyme ImmobilizationEnzymatic ModificationL ‐Amino AcidsRegenerative BiomaterialsBiochemical EngineeringBiodegradable MaterialsBiochemistryBiopolymersBiomolecular EngineeringBiomanufacturingBiotechnologyImmobilized EnzymeMedicineBiomaterialsBiocompatible MaterialEconomical Exploitation
Abstract The immobilization of enzymes, cofactors and whole cells offers the potential of economical exploitation of biomaterial activity. Enzymes or cells can be immobilized by binding to carriers through adsorption or covalent linkages or by entrapment in a polymer matrix or microencapsulation. The development of immobilized biomaterial systems requires the involvement of biochemical, kinetics and reactor design principles. Examples of commercial scale applications of immobilized biomaterial systems are the production of a fructose‐rich syrup from starch and the synthesis of L ‐amino acids by selective hydrolysis of N ‐acyl‐ D , L ‐amino acids.
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