Concepedia

18 F-Fluoride positron emission tomography/computed tomography for noninvasive in vivo quantification of pathophysiological bone metabolism in experimental murine arthritis

Ingo M. Irmler, Peter Gebhardt, Bianca Hoffmann, Thomas Opfermann, Marc Thilo Figge, Hans Peter Saluz, Thomas Kamradt

Arthritis Research & Therapy · 2014 · 27 citations · 14 references

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Abstract

The results of this study suggest that small-animal PET/CT using 18 F-fluoride as a tracer is a feasible method for quantitative assessment of pathophysiological bone metabolism in experimental arthritis. Furthermore, the possibility to perform repeated noninvasive measurements in vivo allows longitudinal study of therapeutical intervention monitoring.

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