Gating of Redox Currents at Gold Nanoelectrodes via DNA Hybridization

Abstract

DNA immobilized at the surface of cone-shaped gold nanoelectrodes provides a favorable platform for artificial ion channels that can gate the redox reaction of ferricyanide. This effect arises from the nanometer-scale curvature and the enhanced mass transfer at nanoelectrodes. The label-free feature based on this ion-channel effect provides a means to develop label-free electrochemical DNA sensors.