<i>MDR1</i> Haplotypes Modify BEN Disease Risk: A Study in Bulgarian Patients with Balkan Endemic Nephropathy Compared to Healthy Controls

Abstract

The data suggest that haplotype 12 is protective against BEN. There is no clear molecular explanation of the MDR1 haplotype effects on the protein activity, which can explain the modified effect of the haplotype 12 on BEN risk.