Cytosol Estrogen Receptors in the Urogenital Tissues in Stress–Incontinent Women

Abstract

function in the pelvic floor. Furthermore the estrogen treatment leads to a significant increase in maximum urethral pressure and urethral length at rest. An effect of estrogens upon the urethra and the periurethral tissues is probab!y mediated by a mechanism of estrogen action similar to that described in other estrogen-sensitive tissues (3). The present communication describes an analysis of estrogen receptors by isoelectric focusing in cytosol from the urethra, pubococcygeal muscle, bladder and vaginal epithelium of patients operated on for stress incontinence.