Wnt Antagonist Gene <i>DKK2</i> Is Epigenetically Silenced and Inhibits Renal Cancer Progression through Apoptotic and Cell Cycle Pathways - Concepedia

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Wnt Antagonist Gene <i>DKK2</i> Is Epigenetically Silenced and Inhibits Renal Cancer Progression through Apoptotic and Cell Cycle Pathways

98

Citations

29

References

2009

Year

Hiroshi Hirata, Yuji Hinoda, Koichi Nakajima, Ken Kawamoto, Nobuyuki Kikuno, Kazumori Kawakami, Soichiro Yamamura, Koji Ueno, Shahana Majid, Sharanjot Saini,

Clinical Cancer Research

Abstract

DKK2 is epigenetically silenced by methylation in higher grades and stages of RCC. These results suggest that DKK2 inhibits renal cancer progression through apoptotic and cell cycle pathways.

References

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