Effects of the Acyl Coenzyme A:Cholesterol Acyltransferase Inhibitor Avasimibe on Human Atherosclerotic Lesions - Concepedia

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Effects of the Acyl Coenzyme A:Cholesterol Acyltransferase Inhibitor Avasimibe on Human Atherosclerotic Lesions

288

Citations

25

References

2004

Year

Jean‐Claude Tardif, Jean Grégoire, Philippe L. L’Allier, Todd J. Anderson, Olivier F. Bertrand, François Reeves, Lawrence Title, Fernándo Alfonso, Érick Schampaert, Alita Hassan,

Abstract

Avasimibe did not favorably alter coronary atherosclerosis as assessed by IVUS. This ACAT inhibitor also caused a mild increase in LDL cholesterol.

References

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Acyl-CoA:Cholesterol Acyltransferase Inhibitor Avasimibe Reduces Atherosclerosis in Addition to Its Cholesterol-Lowering Effect in ApoE*3-Leiden Mice Dianne J. Delsing, Erik H. Offerman, Wim van Duyvenvoorde, Circulation	2001	115
The ACAT Inhibitor Avasimibe Reduces Macrophages and Matrix Metalloproteinase Expression in Atherosclerotic Lesions of Hypercholesterolemic Rabbits Thomas Bocan, Brian R. Krause, Wendy S. Rosebury, Arteriosclerosis Thrombosis and Vascular Biology Vascular DiseaseMatrix Metalloproteinase ExpressionImmunologyPathologyHyperlipidemia	2000	113

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