Neurology · 2014 · 25 citations · 1 references
MedicineInfectious DiseasesNeurologyNeuroinfectious DiseasesPediatric NeurologyVirologyCentral Nervous System InfectionsEncephalitisInfant Infectious DiseasesNeonatal InfectionsViral InfectionsWhite Matter DisordersNeonatal EncephalitisNeurodevelopmental Outcome AssessmentNeurological Viral InfectionsPediatric Central Nervous System InfectionPediatric EncephalitisViral EncephalitisWhite Matter AnatomyWhite Matter Lesions
A full-term 9-day-old girl presented with fever, irritability, and seizures. The routine CSF examination, cranial ultrasound, and laboratory tests were normal. Brain MRI showed diffuse white matter abnormality (figure). Human parechovirus (HPeV) type 3 was isolated in both CSF and blood. The neurodevelopmental outcome at 4 months is poor, and MRI shows an extensive cystic leukomalacia in the frontal white matter.
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