Archives of Ophthalmology · 1967 · 160 citations · 10 references
MedicineOphthalmologyPhysiologyBiomedical OpticsBiophotonicsOcular PathologyPhotoreceptor PhysiologyRetinal AnatomyRetinal ChangesRetinal DegenerationRetinal DiseaseRetinal PathologyLight ExposureMicroscopic CharacterizationOuter Retinal ChangesPhotoreceptor BiologyPhotoreceptor Cell DeathPhotoreceptor DamageRetina HistologyRetinal Physiology
The effect of continuous bright light on the retina of albino rats was studied. It was found that after several hours of exposure the electroretinogram (ERG) deteriorated. However, this phenomenon was found to be reversible. Evidence is presented to show that the deterioration and recovery of the ERG is related to tissue damage and regeneration. Support is given to the theory that the mediating factor in the light damage is chronic visual pigment bleaching.
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Retinal damage by light in rats.
Werner K. Noell, Virgil S. Walker, Bok Soon Kang et al. · PubMed · 1966 · 1.1K citations
Quantum Relations of the Rat Electroretinogram
Richard A. Cone · The Journal of General Physiology · 1963 · 117 citations · Full text
Synthesis and Bleaching of Rhodopsin
George Wald, Paul K. Brown · Nature · 1956 · 107 citations