Solid-state stability study of meropenem – solutions based on spectrophotometric analysis

Abstract

Based on the findings of this work, it appears possible to use time-saving and reliable spectrophotometric analytical methods, supported by quantum-chemical calculations, for solid-state stability investigations of meropenem. The methods developed for this study may be considered a novel, green solution to pharmaceutical analysis of labile drugs - an alternative for the recommended chromatographic procedures.