Concepedia

Publication | Closed Access

Response of Small-Cell Lung Cancer Xenografts to Chemotherapy: Multidrug Resistance and Direct Clinical Correlates

DOI

64

Citations

0

References

1993

Year

M F Poupon, Francisco Arvelo, A Goguel, Yann Bourgeois, M Jacrot, Nicole Hanania, R. Arriagada, Thierry Le Chevalier
JNCI Journal of the National Cancer Institute

Abstract

Failure of chemotherapy to control SCLC seems to be related to an acquired multidrug resistance involving the MDR1-mediated mechanism. Therapeutic benefit could therefore be expected from chemotherapy combined with inhibitors of MDR1.