Effect of the NSAID nimesulide on the radical scavenger glutathione S‑transferase in patients with osteoarthritis of the knee

Abstract

These results confirm the antioxidative properties of the study drug, indicating that nimesulide, beside its known anti-inflammatory properties, also shows an evident antioxidative activity that adds further supportive evidence to its key role in the treatment of OA patients (thanks to the absence of degenerative effects on cartilage).