Solid dispersion: A promising technique to enhance solubility of poorly water soluble drug

Abstract

Poorly water soluble compounds have solubility and dissolution related bioavailability problems. The present review deals in detail about solid dispersion technology and its manufacturing techniques at laboratory and industrial level. This highlight about various hydrophilic polymers used in this technique to enhance solubility of poorly soluble drugs. It also discusses about modern characterization technique to characterize solid dispersion. In this review, it is intended to discuss the recent advances related on the area of solid dispersion technology. Keywords: Solid dispersion; Carriers; Solubility; Dissolution; Bioavailability.