Effects of sevoflurane on intracranial pressure, cerebral blood flow and cerebral metabolism: A dose‐response study in patients subjected to craniotomy for cerebral tumours

Abstract

Sevoflurane is a cerebral vasodilator in patients with cerebral tumours. Sevoflurane increases CBF and decreases CVR in a dose-dependent manner. CO2-reactivity is preserved during 1.5% and 2.5% sevoflurane.