Concepedia

Publication | Closed Access

The First Direct Synthesis of Corroles from Pyrrole

DOI

524

Citations

0

References

1999

Year

Zeev Gross, Nitsa Galili, Irena Saltsman
Angewandte Chemie International Edition

Abstract

The solvent-free, catalyst-free condensation of pyrrole and aldehydes provides an extremely facile synthetic pathway to novel corroles [Eq. (1); Ar=C<sub>6</sub> F<sub>5</sub> , 2,6-F<sub>2</sub> C<sub>6</sub> H<sub>3</sub> , 2,6-Cl<sub>2</sub> C<sub>6</sub> H<sub>3</sub> ]. The product containing pentafluorophenyl groups is an excellent precursor of other derivatives, including an ionic, water-soluble corrole.